Editorial layout demonstration. The following is a short adaptation of the public research introduction, not the full original article.
The question
How does vascular remodelling influence the distribution of stresses in a diseased artery? This work examines that question through patient-specific computational models of atherosclerotic carotids.
A living structure
The study extends the analysis to multiple patients and considers homeostasis-driven growth and remodelling. The model offers a way to investigate how these processes affect vascular stresses.
From patient-specific geometry to a better understanding of vascular mechanics.
Read the full study
The complete methods, results and limitations are available in the original publication.
Alessandro Mastrofini, Christian T. Gasser, Eva Karlöf, Ulf Hedin & Michele Marino.
Journal of the Royal Society Interface, 2025.